JPH0443064B2 - - Google Patents

Info

Publication number
JPH0443064B2
JPH0443064B2 JP58095088A JP9508883A JPH0443064B2 JP H0443064 B2 JPH0443064 B2 JP H0443064B2 JP 58095088 A JP58095088 A JP 58095088A JP 9508883 A JP9508883 A JP 9508883A JP H0443064 B2 JPH0443064 B2 JP H0443064B2
Authority
JP
Japan
Prior art keywords
hydrogen
tetrahydro
isoindoline
formula
carbon atoms
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP58095088A
Other languages
English (en)
Japanese (ja)
Other versions
JPS58225064A (ja
Inventor
Furanshisu Deberunaajisu Jon
Jon Matsukukureran Uiriamu
Josefu Kerukuman Danieru
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott Laboratories
Original Assignee
Abbott Laboratories
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Laboratories filed Critical Abbott Laboratories
Publication of JPS58225064A publication Critical patent/JPS58225064A/ja
Publication of JPH0443064B2 publication Critical patent/JPH0443064B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • C07D209/58—[b]- or [c]-condensed
    • C07D209/62—Naphtho [c] pyrroles; Hydrogenated naphtho [c] pyrroles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • C07D209/58—[b]- or [c]-condensed
    • C07D209/62—Naphtho [c] pyrroles; Hydrogenated naphtho [c] pyrroles
    • C07D209/66—Naphtho [c] pyrroles; Hydrogenated naphtho [c] pyrroles with oxygen atoms in positions 1 and 3

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
JP58095088A 1982-06-01 1983-05-31 テトラヒドロ−ベンゾ〔ｅ〕イソインドリン Granted JPS58225064A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US38363182A 1982-06-01 1982-06-01
US383631 1982-06-01

Publications (2)

Publication Number Publication Date
JPS58225064A JPS58225064A (ja) 1983-12-27
JPH0443064B2 true JPH0443064B2 (en]) 1992-07-15

Family

ID=23514004

Family Applications (1)

Application Number Title Priority Date Filing Date
JP58095088A Granted JPS58225064A (ja) 1982-06-01 1983-05-31 テトラヒドロ−ベンゾ〔ｅ〕イソインドリン

Country Status (10)

Country Link
EP (1) EP0095666B1 (en])
JP (1) JPS58225064A (en])
KR (1) KR900001193B1 (en])
AT (1) ATE40115T1 (en])
AU (1) AU560459B2 (en])
CA (1) CA1215376A (en])
DE (1) DE3378978D1 (en])
ES (1) ES8503329A1 (en])
NZ (1) NZ204213A (en])
ZA (1) ZA833494B (en])

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4622405A (en) * 1984-07-25 1986-11-11 Abbott Laboratories 1,2,3,3a,8,8a-hexahydro-indeno[1,2-c]pyrroles useful in the treatment of hypertension
GR1001059B (el) * 1988-12-15 1993-04-28 Abbott Lab Μεθοδος παραγωγης εκλεκτικων παραγοντων 5-ητ.
ES2090119T3 (es) * 1988-12-15 1996-10-16 Abbott Lab Agentes selectivos de 5-ht.
FR2722194B1 (fr) * 1994-07-06 1996-08-23 Adir Nouveaux derives de benzopyrane, leur procede de preparation et les compositions pharmacuetiques qui les contiennent
US5792767A (en) * 1995-01-27 1998-08-11 Abbott Laboratories Bicyclic substituted hexahydrobenz e! isoindole alpha-1 adrenergic antagonists
ES2168682T3 (es) * 1996-12-06 2002-06-16 Abbott Lab Compuestos alfa-1 adrenergicos a base de benzopiranopirrol y de benzopiranopiridina.
US5891882A (en) * 1996-12-06 1999-04-06 Abbott Laboratories Benzopyranopyrrole and benzopyranopyridine α-1 adenergic compounds

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3166570A (en) * 1963-02-15 1965-01-19 American Home Prod Derivatives of benzo[e] isoindoline and their preparation
EP0003757B1 (de) * 1978-02-08 1981-10-14 Ciba-Geigy Ag Tricyclische Imidylderivate und Verfahren zu ihrer Herstellung
US4282240A (en) * 1979-11-23 1981-08-04 Merck & Co., Inc. Amino substituted tetrahydrobenzindoles

Also Published As

Publication number Publication date
DE3378978D1 (de) 1989-02-23
EP0095666A2 (en) 1983-12-07
KR900001193B1 (ko) 1990-02-28
JPS58225064A (ja) 1983-12-27
ZA833494B (en) 1984-02-29
CA1215376A (en) 1986-12-16
EP0095666B1 (en) 1989-01-18
ES522875A0 (es) 1985-02-16
ATE40115T1 (de) 1989-02-15
AU560459B2 (en) 1987-04-09
ES8503329A1 (es) 1985-02-16
KR840005096A (ko) 1984-11-03
EP0095666A3 (en) 1985-01-16
AU1445283A (en) 1983-12-08
NZ204213A (en) 1986-06-11

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